Computed tomography micromotion analysis of stability of internally fixed femoral neck fractures

Bidragets beskrivning

Fractures of the femoral neck are common and associated with increased need for institutional care and higher mortality. Optimizing the treatment of these fractures can reduce both human suffering and healthcare costs. The purpose of this study is to investigate the osteointegration of femoral neck fractures following surgical treatment. We examine this using a novel micro-motion analysis computed tomography (CTMA) technique. The study is divided into three parts: 1. In Part I, we validate the CTMA method for assessing the healing of femoral neck fractures using a phantom model. 2. Part II is a prospective study in which we monitor fracture healing with CTMA imaging and study the relationship between micro-motion at the fracture site, patient mobilization, and patient reported outcomes. 3. In Part III, we gather a larger, randomized blinded patient cohort and half of the patients receive romosozumab osteoporosis medication. We then evaluate medication's effect on fracture healing.
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Startår

2025

Slutår

2029

Beviljade finansiering

Inari Laaksonen Orcid -palvelun logo
309 042 €

Finansiär

Finlands Akademi

Typ av finansiering

Akademiprojekt

Beslutfattare

Forskningsrådet för biovetenskap, hälsa och miljö
16.06.2025

Övriga uppgifter

Finansieringsbeslutets nummer

371431

Forskningsområden

Kliiniset lääketieteet

Identifierade teman

musculoskeletal diseases