Computed tomography micromotion analysis of stability of internally fixed femoral neck fractures
Bidragets beskrivning
Fractures of the femoral neck are common and associated with increased need for institutional care and higher mortality. Optimizing the treatment of these fractures can reduce both human suffering and healthcare costs. The purpose of this study is to investigate the osteointegration of femoral neck fractures following surgical treatment. We examine this using a novel micro-motion analysis computed tomography (CTMA) technique. The study is divided into three parts: 1. In Part I, we validate the CTMA method for assessing the healing of femoral neck fractures using a phantom model. 2. Part II is a prospective study in which we monitor fracture healing with CTMA imaging and study the relationship between micro-motion at the fracture site, patient mobilization, and patient reported outcomes. 3. In Part III, we gather a larger, randomized blinded patient cohort and half of the patients receive romosozumab osteoporosis medication. We then evaluate medication's effect on fracture healing.
Visa merStartår
2025
Slutår
2029
Beviljade finansiering
Finansiär
Finlands Akademi
Typ av finansiering
Akademiprojekt
Utlysning
Beslutfattare
Forskningsrådet för biovetenskap, hälsa och miljö
16.06.2025
16.06.2025
Övriga uppgifter
Finansieringsbeslutets nummer
371431
Forskningsområden
Kliiniset lääketieteet
Identifierade teman
musculoskeletal diseases