Multi-Modal Data Integration Framework to Overcome Chemotherapy Resistance

Akronym

MULTISTANCE

Bidragets beskrivning

The MULTISTANCE project is aimed at tackling one of the most challenging issues in cancer treatment today: chemotherapy resistance in ovarian high-grade serous carcinoma (HGSC), which is the most prevalent and deadly type of ovarian cancer. At the heart of MULTISTANCE is the development of computational models that combine genomic data from cancer cells with the characteristics of these cells in histopathological images obtained during routine diagnosis. These models leverage a visual language model based on a "Foundation Model," which has been trained on over a million pairs of histopathological images and their clinical descriptions. The model is designed to interpret complex medical images and provide detailed, understandable insights into the cancer's characteristics. The outcome of MULTISTANCE will be publicly available models that are able to integrate multiple types of data and predict chemotherapy outcomes.
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Startår

2025

Slutår

2027

Beviljade finansiering


Sampsa Hautaniemi Orcid -palvelun logo
470 057 €

Rollen i Finlands Akademis konsortium

Övriga parter i konsortiet

Partner
Helsingfors universitet (364982)
260 357 €

Finansiär

Finlands Akademi

Typ av finansiering

Akademiprojekt med särskild inriktning

Beslutfattare

Suomen akatemian muu päättäjä
18.12.2024

Övriga uppgifter

Finansieringsbeslutets nummer

364921

Vetenskapsområden

Biomedicinska vetenskaper

Forskningsområden

Systeemibiologia, bioinformatiikka