Chronic coronary artery disease (CAD) is characterized by coronary artery atherosclerosis that can potentially impair blood supply to heart muscle. The disease is associated with significant morbidity and mortality. Contemporary quantitative imaging methods allow anatomical measurement of atherosclerosis as well as functional measurement of blood flow, and these different imaging methods can complement each other. The rationale of this study is to understand the relative importance of anatomical and functional imaging and their implications to therapy and outcome in CAD. The study includes a real-world cohort of patients who have undergone imaging evaluation for suspected CAD in Turku University Hospital. National registry data on medication purchases are utilized. Patients are followed for clinical events such as myocardial infarction or mortality during several years. The goal is to leverage the potential of imaging to better target current and novel therapies in CAD.

2024

2028