The spatial conformation of large molecules alters their function but is difficult to control. Our team at the University of Jyväskylä investigates whether the shape of large molecules can be controlled by… tying them into knots! With this project, we propose to build large, knotted molecules that mimic the conformations of biological molecules like proteins. We foresee that these synthetic architectures can be used to develop new systems for water desalination, and new gene delivery technologies for cancer treatment and Covid-19 vaccines.

2023

2027