Optimization of boron neutron capture therapy (BNCT) for cancer treatment at Helsinki University Hospital accelerator-based BNCT facility

Bidragets beskrivning

Proton accelerator-based boron neutron capture therapy (BNCT) is a biologically targeted method to treat cancer. BNCT utilizes cancer-seeking boron carrier compounds and neutron irradiation to achieve very high radiation doses to tumors. BNCT may allow treating of otherwise difficult-to-treat cancers effectively. The first accelerator-based BNCT facility in Europe has been built on the Meilahti Academic Medicine Center campus, and it is the first facility in the world that is closely integrated with a large hospital radiation therapy department. This places Finland in the forefront in the development of BNCT. In this study, we aim to develop new tools for measuring accuracy of radiation dose delivery with BNCT to cancer, participate in research on novel boron carrier compounds, and initiate and conduct clinical trials to treat e.g. patients who face unfavorable survival outcomes with the currently available cancer treatments.
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Startår

2023

Slutår

2027

Beviljade finansiering

Mikko Juhani Tenhunen Orcid -palvelun logo
437 960 €

Finansiär

Finlands Akademi

Typ av finansiering

Akademiprojekt

Beslutfattare

Forskningsrådet för naturvetenskap och teknik
06.06.2023

Övriga uppgifter

Finansieringsbeslutets nummer

355100

Vetenskapsområden

Fysik

Forskningsområden

Fysiikka

Identifierade teman

cancer