Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"

Beskrivning

This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.
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Publiceringsår

2020

Typ av data

Upphovspersoner

4TU.ResearchData - Utgivare

Eindhoven University of Technology

Sandra Loerakker - Upphovsperson

Tommaso Ristori - Upphovsperson

Cecilia Sahlgren Orcid -palvelun logo - Upphovsperson

Oscar Stassen - Upphovsperson

Projekt

Övriga uppgifter

Vetenskapsområden

Biokemi, cell- och molekylärbiologi

Språk

Öppen tillgång

Öppet

Licens

Creative Commons Attribution 4.0 International (CC BY 4.0)

Nyckelord

Biomedical Engineering, FOS: Medical engineering, Notch signaling, agent-based model, growth and remodeling, artery, jagged, lateral induction, Time: 2020

Ämnesord

Temporal täckning

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