eUTOPIA: solUTion for Omics data PreprocessIng and Analysis

Beskrivning

Abstract Background Application of microarrays in omics technologies enables quantification of many biomolecules simultaneously. It is widely applied to observe the positive or negative effect on biomolecule activity in perturbed versus the steady state by quantitative comparison. Community resources, such as Bioconductor and CRAN, host tools based on R language that have become standard for high-throughput analytics. However, application of these tools is technically challenging for generic users and require specific computational skills. There is a need for intuitive and easy-to-use platform to process omics data, visualize, and interpret results. Results We propose an integrated software solution, eUTOPIA, that implements a set of essential processing steps as a guided workflow presented to the user as an R Shiny application. Conclusions eUTOPIA allows researchers to perform preprocessing and analysis of microarray data via a simple and intuitive graphical interface while using state of the art methods.
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Publiceringsår

2019

Typ av data

Upphovspersoner

Angela Serra - Upphovsperson

Dario Greco - Upphovsperson

Veer Singh Marwah - Upphovsperson

Unknown organization

Giovanni Scala - Upphovsperson

Harri Alenius - Upphovsperson

Pia Anneli Sofia Kinaret - Upphovsperson

Vittorio Fortino - Upphovsperson

figshare - Utgivare

Projekt

Övriga uppgifter

Vetenskapsområden

Medicinsk bioteknologi

Språk

engelska

Öppen tillgång

Öppet

Licens

Creative Commons Attribution 4.0 International (CC BY 4.0)

Nyckelord

genetics, Biotechnology, 19999 Mathematical Sciences not elsewhere classified, FOS: Biological sciences, 69999 Biological Sciences not elsewhere classified, FOS: Mathematics, FOS: Computer and information sciences, Space Science, 80699 Information Systems not els

Ämnesord

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