Antimicrobial resistance (AMR) is a global health crisis contributing to 1 million deaths annually, with disproportionate mortality in children, the elderly, and low- and middle-income countries. The Expanding the Horizons of Antimicrobial Resistance Research (EHAR) project will enhance knowledge on AMR in the human gut microbiome by 1) including data from under-studied populations, such as children, the elderly, and low-income populations and 2) incorporating methods that are underutilized in AMR research, including metagenomics, long-read sequencing, and cutting-edge data science 3) significantly increasing the scope of global AMR research by utilizing a big data approach covering over 18,000 samples from Finnish and Indian population cohorts and 58,037 AMR profiles from openly available human gut metagenomes. EHAR will spearhead new directions in AMR research and help mitigate the AMR crisis in the long term.

2025

2029