Microbes contribute to human health, and a microbial shift to an unbalanced direction has shown to play a role in chronic diseases. Oral microbiota and oral infections may influence systemic inflammation. The objective is to find evidence on salivary microbiome contributing to the occurrence of cryptogenic ischemic stroke in patients younger than 50 years. Patients with stroke and their matched controls are investigated in a case-control study. Oral infections and salivary microbiota will be investigated in order to find changes possibly contributing to stroke. This project will provide novel information on oral risk factors for cryptogenic stroke at younger ages.

2023

2027