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Publicationer information ikon

Punahometta aiheuttavan Fusarium-sienen seriiniproteinaasit ja niiden inhibiittorit

Pekkarinen, Anja
Mallas ja Olut2003Publicationer information ikon

Discovery of a Noncompetitive Open-Flap Selective Inhibitor of Plasmepsin II with Antiplasmodial Activity

Referentgranskad
DOI
10.1021/acs.jcim.4c02059
Valiente, Pedro A.; Guerra, Yasel; Wolf, Maarten G.; Pascual, Isel; Rudiño-Piñera, Enrique; Florent,...
Journal of Chemical Information and Modeling2025Publicationer information ikon

Structural insight of PP2A inhibitor proteins and their interaction with PP2A Aand B56-subunits

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Thapa, Chandan Jung
JYU Dissertations2021Publicationer information ikon

New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights

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DOI
10.1080/14756366.2023.2281260
Barakat, Assem; Alshahrani, Saeed; Al-Majid, Abdullah Mohammed; Alamary, Abdullah Saleh; Haukka, Mat...
Journal of Enzyme Inhibition and Medicinal Chemistry2023Publicationer information ikon

Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer cells

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DOI
10.3389/fchem.2024.1364378
Nafie, Mohamed S.; Al-Majid, Abdullah Mohammed; Ali, M.; Alayyaf, Abdulmajeed Abdullah; Haukka, Matt...
Frontiers in Chemistry2024Publicationer information ikon

Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ

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DOI
10.1128/spectrum.00552-23
Laajala, Mira; Zwaagstra, Marleen; Martikainen, Mari; Nekoua, Magloire Pandoua; Benkahla, Mehdi; San...
Microbiology spectrum2023Publicationer information ikon

Interaction mechanism of endogenous PP2A inhibitor protein ENSA with PP2A

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DOI
10.1111/febs.16150
Thapa, Chandan; Roivas, Pekka; Haataja, Tatu; Permi, Perttu; Pentikäinen, Ulla
Febs journal2022Publicationer information ikon

Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors

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DOI
10.1021/acsomega.1c03978
Islam, Mohammad Shahidul; Al-Majid, Abdullah Mohammed; Azam, Mohammad; Verma, Ved Prakash; Barakat, ...
ACS Omega2021Publicationer information ikon

A novel alpha-amylase inhibitor-based spirooxindole-pyrrolidine-clubbed thiochromene-pyrzaole pharmacophores : Unveiling the [3+2] cycloaddition reaction by molecular electron density theory

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DOI
10.1111/cbdd.14299
Islam, Mohammad Shahidul; Al‐Majid, Abdullah Mohammed; Haukka, Matti; Parveen, Zahida; Ravaiz, Nabee...
Chemical Biology and Drug Design2023Publicationer information ikon

Microwave-assisted synthesis and in vitro and in silico studies of pyrano[3,2-c]quinoline-3-carboxylates as dual acting anti-cancer and anti-microbial agents and potential topoisomerase II and DNA-gyrase inhibitors

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DOI
10.1039/d4ra06201a
Aly, Ashraf A.; Abd, El-Naby Hisham A.; Ahmed, Essam Kh.; Gedamy, Sageda A.; Rissanen, Kari; Nieger,...
Rsc advances2025

Punahometta aiheuttavan Fusarium-sienen seriiniproteinaasit ja niiden inhibiittorit

2003

Discovery of a Noncompetitive Open-Flap Selective Inhibitor of Plasmepsin II with Antiplasmodial Activity

Referentgranskad
DOI
10.1021/acs.jcim.4c02059
2025

Structural insight of PP2A inhibitor proteins and their interaction with PP2A Aand B56-subunits

Öppen tillgång
2021

New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights

Referentgranskad
Öppen tillgång
DOI
10.1080/14756366.2023.2281260
2023

Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer cells

Referentgranskad
Öppen tillgång
DOI
10.3389/fchem.2024.1364378
2024

Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ

Referentgranskad
Öppen tillgång
DOI
10.1128/spectrum.00552-23
2023

Interaction mechanism of endogenous PP2A inhibitor protein ENSA with PP2A

Referentgranskad
Öppen tillgång
DOI
10.1111/febs.16150
2022

Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors

Referentgranskad
Öppen tillgång
DOI
10.1021/acsomega.1c03978
2021

A novel alpha-amylase inhibitor-based spirooxindole-pyrrolidine-clubbed thiochromene-pyrzaole pharmacophores : Unveiling the [3+2] cycloaddition reaction by molecular electron density theory

Referentgranskad
DOI
10.1111/cbdd.14299
2023

Microwave-assisted synthesis and in vitro and in silico studies of pyrano[3,2-c]quinoline-3-carboxylates as dual acting anti-cancer and anti-microbial agents and potential topoisomerase II and DNA-gyrase inhibitors

Referentgranskad
Öppen tillgång
DOI
10.1039/d4ra06201a
2025