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Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment

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DOI
10.1021/acsmedchemlett.9b00537
Johansson, Niklas G; Turku, Ainoleena; Vidilaseris, Keni; Dreano, Loic; Khattab, Ayman; Ayuso Perez,...
Acs medicinal chemistry letters2020Publicationer information ikon

Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation

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DOI
10.1063/1.4978038
Shah, Nita R.; Wilkinson, Craig; Harborne, Steven P. D.; Turku, Ainoleena; Li, Kun-Mou; Sun, Yuh-Ju;...
Structural dynamics2017Publicationer information ikon

Asymmetry in catalysis by Thermotoga maritima membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor

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DOI
10.1126/sciadv.aav7574
Vidilaseris, Keni; Kiriazis, Alexandros; Turku, Ainoleena; Khattab, Ayman Abdelnaby Shaaban; Johanss...
Science advances2019Publicationer information ikon

A high-throughput method for orthophosphate determination of thermostable membrane-bound pyrophosphatase activity

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DOI
10.1039/c7ay02558k
Vidilaseris, Keni; Kellosalo, Juho; Goldman, Adrian
Analytical Methods2018Publicationer information ikon

Exploration of Pyrazolo[1,5-a]pyrimidines as Membrane-Bound Pyrophosphatase Inhibitors

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DOI
10.1002/cmdc.202100392
Johansson, Niklas G; Dreano, Loic; Vidilaseris, Keni; Khattab, Ayman; Liu, Jianing; Lasbleiz, Arthur...
Chemmedchem2021

Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment

Referentgranskad
Öppen tillgång
DOI
10.1021/acsmedchemlett.9b00537
2020

Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation

Referentgranskad
Öppen tillgång
DOI
10.1063/1.4978038
2017

Asymmetry in catalysis by Thermotoga maritima membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor

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DOI
10.1126/sciadv.aav7574
2019

A high-throughput method for orthophosphate determination of thermostable membrane-bound pyrophosphatase activity

Referentgranskad
Öppen tillgång
DOI
10.1039/c7ay02558k
2018

Exploration of Pyrazolo[1,5-a]pyrimidines as Membrane-Bound Pyrophosphatase Inhibitors

Referentgranskad
Öppen tillgång
DOI
10.1002/cmdc.202100392
2021